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PROGRAM
Microbicides

Nonclinical Laboratory Studies

The Population Council conducts basic research on the sexual transmission of HIV and the immunological processes involved, as well as reproductive biology, which serves as the basis for the development of new AIDS-prevention products and contraceptive methods.

The Council's candidate microbicides are at different stages of development and testing. Its microbicide candidate, Carraguard®, has completed its Phase 3 clinical trial to assess long-term safety and effectiveness. (results)

Newer formulations are in earlier stages of testing.

Projects, Nonclinical Studies


See Also

Contact: microbicide@popcouncil.org



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This page updated
3 December 2008


   

What's New

HIV prevention news: PRO 2000, a candidate microbicide developed by Indevus Pharmaceuticals, Inc., and tested in a clinical trial in six countries on two continents, was found to be safe and to have reduced the risk of HIV infection by 30 percent. While not statistically significant, this finding was welcomed by the HIV-prevention field as an optimistic sign for future success. (more

The Lancet’s 6 December issue features results from the Phase 3 trial of Carraguard®. (Trial results were announced previously by the Population Council in February 2008.) (more) For fact sheets and other resources about the Carraguard trial, click here

Presentations at the Microbicides 2008 conference in New Delhi by Council researchers are available. (more)

"Benefits of the Population Council's microbicides program and Phase 3 Carraguard trial" (2008) (PDFs: A4 and letter)

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Publications/Resources

"Relative safety of sexual lubricants for rectal intercourse" (2004) (abstract)

"Assay for establishing whether microbicide applicators have been exposed to the vagina" (2004) (abstract)

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