Population Council | Microbicides

PROGRAM
Microbicides

What Comes Next

Population Council biomedical scientists are continuing basic research on HIV transmission and are working on developing microbicide formulations that may be more effective against a broader range of sexually transmitted pathogens and/or have contraceptive properties.

If future trials prove successful and one of the Council's candidate microbicides is shown to be safe and effective, additional steps will have to be taken before the product is available to consumers. Product approvals would have to be secured through the regulatory bodies of the countries in which the product would be marketed; and agreements would be needed for production and distribution.

If a successful microbicide were based on Carraguard, the abundance of carrageenan—a naturally occurring substance derived from seaweed—should make it a low-cost ingredient, helping keep the product as inexpensive as possible.

Historically, the Population Council has developed safe, effective contraceptives and worked to make them available at very low (or no) cost to people in developing countries. (For instance, more than 76 million Copper T 380A IUDs have been distributed in over 70 countries, most at very nominal costs to the user.) The Council accomplishes this by including provisions for low-cost access to the products when licensing its contraceptive products to pharmaceutical companies for manufacture and marketing. Alternatively, a charitable foundation may be created to donate the product. Any agreement with a firm regarding microbicides would contain similar provisions, and any royalties that the Council would earn from the development of a successful microbicide would be reinvested into future public health research projects.

The Population Council is committed to working with funding organizations and international public health institutions—such as the World Bank, the United Nations, and the US Agency for International Development—to facilitate the accessibility and affordability of these products in the developing world. In fact, making microbicides available where they are most needed is a primary goal of the organization.

Carraguard® is the Population Council's US trademark for pharmaceutical preparations, namely microbicides, for use in preventing HIV infection.

(back to History of Research)