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OCEANIA The Council and the Australia-based pharmaceuticals company Acrux Limited are collaborating on the development of a transdermal contraceptive spray. The Population Council granted to Acrux a worldwide license to intellectual property covering the use of Nestorone®, a fourth-generation progestin extensively researched by the Population Council. A Phase 1, proof-of-concept, pharmacokinetic study conducted in six healthy women was completed in 2005. Ian Stewart Fraser, professor in reproductive medicine at the University of Sydney, Australia, and a member of the Population Council's International Center for Contraception Research, was a co-principal investigator for the Phase 1 trial. A Phase 2 trial, scheduled to begin in the second half of 2006, aims to demonstrate that the spray inhibits ovulation. In addition, the Population Council approved an award to the University of Sydney (Center for Virus Research, Westmead Millennium Institute) to support a project entitled “Dendritic cell defensin and type I IFN responses in HIV," with Anthony Cunningham as principal investigator of the consortium research, and Melissa Robbiani (Pope) of the Population Council's Center for Biomedical Research as overall principal investigator. Publications/Resources 2004 2003 See Also
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