Emergency Contraceptive Potential of Products Under Development
Many contraceptive products may have utility as emergency contraceptive methods; the Council is evaluating the potential of selected candidate products.
Population Council scientists and members of its International Committee for Contraception Research staff evaluate the emergency contraceptive potential of contraceptive products under development. The Nestorone®/ethinyl estradiol (EE) ring is being evaluated to determine at what point in the menstrual cycle insertion of this ring may affect follicular maturation, the goal being to determine whether insertion late in the menstrual cycle can inhibit ovulation.
This approach may lead to a method that a woman can use for emergency contraception, then continue to use, following menses, as a regular contraceptive method. The results of one study indicate that the Nestorone/EE contraceptive ring is a promising new approach for emergency contraception with a number of advantages.
The length of the menstrual cycle is reduced in a large proportion of women, thus reducing the time a woman has to wait to determine whether or not she is pregnant. Delayed ovulation did not occur after the one week of ring use; therefore, if subsequent unprotected intercourse were to occur in the treatment cycle, there would be no risk of pregnancy. No serious adverse events were reported during the study. Expanded efficacy trials are necessary to confirm the effectiveness of this new treatment and to evaluate side effects. A low-cost product is dependent on the simultaneous development of this vaginal ring as a contraceptive product.
Key opinion leaders' views regarding emergency contraception in India (PDF)
Khan,M.E.; Bhatnagar,Isha; Varma,Deepthi S.; Dixit,Anvita
Program brief, February 2012
Publication date: 2012
Providers' and key opinion leaders' attitudes and practices regarding emergency contraception in Senegal: Key findings (PDF)
Mane,Babacar; Brady,Martha; RamaRao,Saumya; Bintou Mbow,Fatou
Program brief, February 2012
Publication date: 2012
Providers' and key opinion leaders' attitudes, beliefs, and practices concerning emergency contraception: A multicountry study in India, Nigeria, and Senegal (PDF)
Brady,Martha; Khan,M.E.; Ahonsi,Babatunde; Mane,Babacar; Askew,Ian; RamaRao,Saumya
Program brief, February 2012
Publication date: 2012
Providers' and key opinion leaders' attitudes, beliefs, and practices regarding emergency contraception in Nigeria: Key findings (PDF)
Ahonsi,Babatunde; Salisu,Ishaku; Idowu,Araoyinbo; Oginni,Ayo
Program brief, February 2012
Publication date: 2012
Providers' attitudes and practices regarding emergency contraception in India: Key findings (PDF)
Khan,M.E.; Bhatnagar,Isha; Varma,Deepthi S.; Dixit,Anvita
Program brief, February 2012
Publication date: 2012
Pharmacokinetic study to compare the absorption and tolerability of two doses of levonorgestrel following single vaginal administration of levonorgestrel in Carraguard® gel: A new formulation for 'dual protection' contraception (abstract)
Sitruk-Ware,Regine; Brache,Vivian; Maguire,Robin A.; Croxatto,Horacio B.; Kumar,Narender; Kumar,Sushma; Montero,Juan Carlos; Salvatierra,Ana Maria; Phillips,David M.; Faundes,Anibal
Contraception 75(6): 454-460
Publication date: 2007
Pharmacokinetic study of different dosing regimens of levonorgestrel for emergency contraception in healthy women (abstract)
Johansson,Elof D.B.; Brache,Vivian; Alvarez-Sanchez,Francisco; Faundes,Anibal; Cochon,Leila; Ranta,Sirpa; Lovern,Mark; Kumar,Narender
Human Reproduction 17(6): 1472-1476
Publication date: 2002
Project Stats
Location: United States
Program(s):
Reproductive Health
Topic(s):
Technologies for women
Duration: 1/2005 - ongoing
Population Council researchers:
Régine Sitruk-Ware
Donors:
The George J. Hecht Fund
The Lita Annenberg Hazen Foundation
The William and Flora Hewlett Foundation
US Agency for International Development
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