Abstract
Mifepristone and misoprostol sequential regimen side effects, complications and safety (HTML)
Sitruk-Ware,Regine
Contraception 74(1): 48-55
Publication date: 2006
Exhibiting a strong affinity to the progesterone and the glucocorticoid receptors, mifepristone exert competitive antagonism to these hormones both in in vitro and in animal experiments. Due to its antiprogesterone activity, it was proposed that mifepristone be used for the termination of early human pregnancy. Mifepristone, at a dose of 600 mg initially used alone, was then used with a subsequent low dose of prostaglandin that led to a success rate of 95% as a medical method for early termination of pregnancy (TOP), and the occurrence of continuing pregnancy was reduced to
What's New
For 60 years, the Population Council has changed the way the world thinks about important health and development issues. Explore an interactive timeline of the Council's history, learn more about some of our key contributions, and watch a short video about why your support is so important to us.
Get Involved
- Make a contribution to the Population Council
- Honor a loved one with a gift in his or her name
- Sign up to receive e-mail announcements
Connect
