Abstract
Transcription regulation in spermatogenesis
Lui,Wing-Yee; Cheng,Chuen-yan
Advances in Experimental Medicine and Biology 636 115-132
Publication date: 2009
Spermatogenesis is a highly coordinated process in which diploid spermatogonia (2n) differentiate into mature haploid (1n) spermatozoa in the seminiferous epithelium. In this process, spermatogonia undergo several mitotic divisions and either enter a stem cell renewal pathway, or commit themsevles for further development. Diploid spermatocytes subsequently undergo two meiotic divisions and result in the production of haploid round spermatids. They then enter the process of spermiogenesis in which profound morphological and biochemical restructuring, such as the formation of acrosome and flagellum occur, and give rise to mature spermatozoa.
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