Population Council Research that makes a difference

Barbara Friedland, M.P.H.

Associate

Barbara Friedland, an associate in the Population Council's HIV and AIDS program, has been integrally involved in the Council’s microbicides program since 1996, conducting both clinical and behavioral research. She was the study coordinator for several clinical trials of Carraguard®, the Council’s candidate microbicide, and directed the behavioral aspects of the Council’s Phase 3 efficacy trial of Carraguard. In this role, she was responsible for the development of informed consent and educational materials, including a 20-minute educational video produced in four languages for the three South African study sites. (She talks about the process in a short video.) Most recently, she produced a video entitled Hope Against HIV: Microbicides Trials in Your Community for use educating communities in Africa about microbicide clinical trials.

Friedland's portfolio includes quantitative and qualitative research on ethical issues in HIV prevention research, informed consent for male circumcision service delivery, and behavioral studies around microbicides acceptability and adherence. Prior to joining the Council, she was orchestra manager for the New York City–based Orpheus Chamber Orchestra and business affairs and public relations manager at Open City Films.

Friedland received her master's in public health in community health education from Hunter College of the City University of New York. A graduate of Douglass College, Rutgers University, she holds a master's of music in piano performance from the Mason Gross School of the Arts, Rutgers University. She has also produced several films, including a documentary entitled From Coercion to Choice: The Hysterectomy Epidemic in America.

Barbara Friedland, M.P.H.

Associate

Male Circumcision Partnership: Achieving Scale (more)
The Male Circumcision Partnership is establishing multisectoral provider networks for high-quality adult male circumcision services.
(1/2009 - 11/2013)
Topics: Male circumcision; Sexuality and sexual behavior
Countries: Swaziland, Zambia

A Simulated Clinical Trial to Explore Willingness to Participate and Methods for Improving Reporting of Adherence Among a Sex-worker Cohort in Nellore, India (more)
A simulated microbicides clinical study is being conducted in India to develop and test strategies for improving recruitment, adherence, and the reporting of adherence for future microbicides clinical trials.
(1/2008 - 1/2012)
Topics: Microbicides; Sex workers
Countries: India

Clinical Studies: Carraguard® Phase 3 Clinical Trial (more)
Council researchers completed Phase 3 testing of the Council’s candidate microbicide Carraguard.
(3/2004 - 3/2007)
Topics: Microbicides
Countries: South Africa

Barbara Friedland, M.P.H.

Associate

An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India  (abstract) (HTML
Abbott,Sharon; Friedland,Barbara A.; Sarna,Avina; Katzen,Lauren L.; Rawiel,Ulrike; Srikrishnan,Aylur K.; Shalini,C.S.; Tun,Waimar; Kelly,Christine A.; Solomon,Suniti; Mensch,Barbara S.
AIDS and Behavior 17(6): 2222-2236
Publication date: 2013

Characteristics of female sex workers in southern India willing and unwilling to participate in a placebo gel trial  (abstract) (HTML
Mensch,Barbara S.; Friedland,Barbara A.; Abbott,Sharon; Katzen,Lauren L.; Tun,Waimar; Kelly,Clifton A.; Sarna,Avina; Srikrishnan,Aylur K.; Solomon,Suniti
AIDS and Behavior 17(2): 585-597
Publication date: 2013

How informed are clients who consent? A mixed-method evaluation of comprehension among clients of male circumcision services in Zambia and Swaziland  (abstract) (HTML
Friedland,Barbara A.; Apicella,Louis; Schenk,Katie D.; Sheehy,Meredith; Hewett,Paul C.
AIDS and Behavior 17(6): 2269-2282
Publication date: 2013

Microbicide clinical trial adherence: Insights for introduction  (abstract) (PDF
Woodsong,Cynthia; MacQueen,Kathleen M.; Amico,K.Rivet; Friedland,Barbara A.; Gafos,Mitzy; Mansoor,Leila; Tolley,Elizabeth E.; McCormack,Sheena
Journal of the International AIDS Society 16: 18505-
Publication date: 2013

Sexually transmitted infections and reproductive health morbidity in a cohort of female sex workers screened for a microbicide feasibility study in Nellore, India  (abstract) (HTML
Sarna,Avina; Friedland,Barbara A.; Srikrishnan,Aylur K.; Katzen,Lauren L.; Tun,Waimar; Abbott,Sharon; Rawiel,Ulrike; Kelly,Christine A.; Shalini,C.S.; Solomon,Suniti; Mensch,Barbara S.
Global Journal of Health Science 5(3): 139-149
Publication date: 2013

Hormonal contraception and the risk of HIV acquisition among women in South Africa  (abstract) (HTML
Morrison,Charles S.; Skoler-Karpoff,Stephanie; Kwok,Cynthia; Chen,Pai-lien; van de Wijgert,Janneke; Gehret-Plagianos,Marlena; Patel,Smruti; Ahmed,Khatija; Ramjee,Gita; Friedland,Barbara A.; Lahteenmaki,Pekka
AIDS 26(4): 497-504
Publication date: 2012

On the cutting edge: Improving the informed consent process for adolescents in Zambia undergoing male circumcision for HIV prevention  (abstract) (HTML
Schenk,Katie D.; Friedland,Barbara A.; Apicella,Louis; Sheehy,Meredith; Munjile,Kelvin; Hewett,Paul C.
Vulnerable Children and Youth Studies 7(2): 116-127
Publication date: 2012

Acceptability of Carraguard vaginal microbicide gel among HIV-infected women in Chiang Rai, Thailand  (abstract) (HTML
Whitehead,Sara J.; McLean,Catherine A.; Chaikummao,Supaporn; Braunstein,Sarah; Utaivoravit,Wat; van de Wijgert,Janneke; Mock,Philip A.; Siraprapasiri,Taweesap; Friedland,Barbara A.; Kilmarx,Peter H.; Markowitz,Lauri
PLoS ONE 6(9): e14831-
Publication date: 2011

Evaluation of the informed consent process for male circumcision scale-up in Swaziland  (PDF
Friedland,Barbara A.; Apicella,Louis; Schenk,Katie D.; Sheehy,Meredith; Hewett,Paul C.
Population Council Research and Evaluation of Male Circumcision Scale-up Report (no. 3)
Publication date: 2011

Evaluation of the informed consent process for male circumcision scale-up in Zambia  (PDF
Friedland,Barbara A.; Apicella,Louis; Schenk,Katie D.; Sheehy,Meredith; Hewett,Paul C.
Population Council Research and Evaluation of Male Circumcision Scale-Up Report (no. 1)
Publication date: 2011

"Microbicides trials in your community," video 
Summers,Fiona; Friedland,Barbara A.
Publication date: 2009

Acceptability of a Carrageenan-based candidate vaginal microbicide and matching placebo: Findings from a phase II safety trial among women in Chiang Rai, Thailand  (abstract) (HTML
Jones,Heidi E.; Chaikummao,Supaporn; van de Wijgert,Janneke; Friedland,Barbara A.; Manopaiboon,Chomnad; Witwatwongwana,Paisit; Wankrairoj,Mayuree; Chantharojwong,Nartlada; Kilmarx,Peter H.
Journal of Women's Health 18(7): 1003-1010
Publication date: 2009

Vaginal microbicide adherence biomarkers should be validated--Authors' reply  (HTML
Skoler-Karpoff,Stephanie; Friedland,Barbara A.; Plagianos,Marlena Gehret; Maguire,Robin A.; Lahteenmaki,Pekka
Lancet 373(9665): 721-722
Publication date: 2009

A randomized, placebo-controlled trial to assess the safety and acceptability of use of Carraguard vaginal gel by heterosexual couples in Thailand  (abstract) (HTML
Kilmarx,Peter H.; Blanchard,Kelly; Chaikummao,Supaporn; Friedland,Barbara A.; Srivirojana,Nucharee; Connolly,Cathy; Witwatwongwana,Paisit; Supawitkul,Somsak; Mock,Philip A.; Chaowanachan,Thanyanan; Tappero,Jordan W.
Sexually Transmitted Diseases 35(3): 226-232
Publication date: 2008

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial  (abstract) (HTML
Skoler-Karpoff,Stephanie; Ramjee,Gita; Ahmed,Khatija; Altini,Lydia; Gehret,Marlena; Friedland,Barbara A.; Govender,Sumentheran N.; de Kock,Alana; Cassim,Nazira; Palanee,Thesla; Dozier,Gregory; Maguire,Robin A.; Lahteenmaki,Pekka
Lancet 372(9654): 1977-1987
Publication date: 2008

A question of ethics: Research and practice in reproductive health  (abstract) (PDF
RamaRao,Saumya; Friedland,Barbara A.; Townsend,John W.
Studies in Family Planning 38(4): 229-241
Publication date: 2007

Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa  (abstract) (PDF
Ramjee,Gita; Morar,Neetha S.; Braunstein,Sarah; Friedland,Barbara A.; Jones,Heidi E.; van de Wijgert,Janneke
AIDS Research and Therapy 4(20)
Publication date: 2007

Carraguard vaginal gel safety in HIV-positive women and men in South Africa  (abstract) (HTML
van de Wijgert,Janneke; Braunstein,Sarah; Morar,Neetha S.; Jones,Heidi E.; Madurai,Lorna; Evans Strickfaden,Tammy T.; Moodley,Manivasan; Aboobaker,Jamila; Ndlovu,Gugulethu; Ferguson,Taja M.; Friedland,Barbara A.; Hart,Clyde E.; Ramjee,Gita
Journal of Acquired Immune Deficiency Syndromes 46(5): 538-546
Publication date: 2007

Acceptability of Carraguard vaginal gel use among Thai couples  (abstract) (HTML
Whitehead,Sara J.; Kilmarx,Peter H.; Blanchard,Kelly; Manopaiboon,Chomnad; Chaikummao,Supaporn; Friedland,Barbara A.; Achalapong,Jullapong; Wankrairoj,Mayuree; Mock,Philip A.; Thanprasertsuk,Sombat; Tappero,Jordan W.
AIDS 20(17): 2141-2148
Publication date: 2006

Informed Consent in HIV Prevention Trials: Report of an International Workshop  (PDF
McGrory,C.Elizabeth; Friedland,Barbara A.; Woodsong,Cynthia; MacQueen,Kathleen M.
Publication date: 2006

Safety and acceptability of the candidate microbicide Carraguard in Thai women: Findings from a Phase II clinical trial  (abstract) (HTML
Kilmarx,Peter H.; van de Wijgert,Janneke; Chaikummao,Supaporn; Jones,Heidi E.; Limpakarnjanarat,Kanchit; Friedland,Barbara A.; Karon,John M.; Manopaiboon,Chomnad; Srivirojana,Nucharee; Yanpaisarn,Somboonsak; Supawitkul,Somsak; Young,Nancy L.; Mock,Philip A.; Blanchard,Kelly; Mastro,Timothy D.
Journal of Acquired Immune Deficiency Syndromes 43(3): 327-334
Publication date: 2006

Phase III microbicide trial methodology: Opinions of experienced expanded safety trial participants in South Africa  (abstract) (PDF) (HTML
van de Wijgert,Janneke; Jones,Heidi E.; Pistorius,Annalie; de Kock,Alana; Sebola,Mohlatlego H.; Friedland,Barbara A.; Hoosen,Anwar; Coetzee,Nicol
Journal of Social Aspects of HIV/AIDS 2(3): 311-319
Publication date: 2005

Microbicide trials for preventing HIV/AIDS in South Africa: Phase II trial participants' experiences and psychological needs  (abstract) (PDF) (HTML
Pistorius,Annalie; van de Wijgert,Janneke; Sebola,Mohlatlego H.; Friedland,Barbara A.; Nagel,Evelyn; Bokaba,Cathleen; Hoosen,Anwar
Journal of Social Aspects of HIV/AIDS 1(2): 78-86
Publication date: 2004

Testing Carraguard: What you need to know  (PDF
Clacherty,Glynis; Friedland,Barbara A.; de Kock,Alana; Marumo,Mabitso
Publication date: 2004

Informed consent: From good intentions to sound practices--A report of a seminar  (PDF
Wood,Susan Y.; Friedland,Barbara A.; McGrory,C.Elizabeth
Robert H. Ebert Program on Critical Issues in Reproductive Health Publication Series
Publication date: 2002

Acceptability and feasibility of Micralax applicators and of methyl cellulose gel placebo for large-scale clinical trials of vaginal microbicides  (abstract) (PDF
Coetzee,Nicol; Blanchard,Kelly; Ellertson,Charlotte; Hoosen,Anwar; Friedland,Barbara A.
AIDS 15(14): 1837-1842
Publication date: 2001

Men's attitudes towards a potential vaginal microbicide in Zimbabwe, Mexico and the USA  (abstract) (PDF) (HTML
Coggins,Christiana; Blanchard,Kelly; Friedland,Barbara A.
Reproductive Health Matters 8(15): 132-141
Publication date: 2000

Barbara Friedland, M.P.H.

Associate

"He died because it was traditionally done at the pit 'Muganda,' so...that gave me fear" -- The impact of traditional circumcision on the scale-up of male circumcision services in Zambia (abstract) (PDF
Poster presentation at the 6th International AIDS Society Conference, Rome, Italy, 17-20 July
Friedland,Barbara A.; Schenk,Katie D.; Sheehy,Meredith; Munjile,Kelvin; Apicella,Louis; Hewett,Paul C.
Publication date: 2011

A cut above? Evidence-based lessons for improving the informed consent process for male circumcision in Swaziland and Zambia (abstract)  
Presentation at the American Public Health Association 139th Annual Meeting and Exposition, Washington DC, 29 October-2 November
Schenk,Katie D.; Friedland,Barbara A.; Apicella,Louis; Sheehy,Meredith; Munjile,Kelvin; Hewett,Paul C.
Publication date: 2011

Assessing comprehension of key informed consent concepts among clients undergoing male circumcision during scale-up of services in Zambia and Swaziland (abstract) (PDF
Poster presentation at the 19th meeting of the International Society for Sexually Transmitted Diseases Research, Quebec City, 10-13 July
Friedland,Barbara A.; Apicella,Louis; Sheehy,Meredith; Schenk,Katie D.; Munjile,Kelvin; Adams,Alfred; Hewett,Paul C.
Publication date: 2011

Impact of a comprehension assessment among adult and adolescent clients on scale up of male circumcision services in Zambia (abstract) (PDF
Poster presentation at the 6th International AIDS Society Conference, Rome, Italy, 17-20 July
Friedland,Barbara A.; Apicella,Louis; Sheehy,Meredith; Schenk,Katie D.; Munjile,Kelvin; Adams,Alfred; Hewett,Paul C.; Katzen,Lauren L.
Publication date: 2011

On the cutting edge: Research to improve the informed consent process for adolescents in Zambia undergoing male circumcision for HIV prevention (abstract)  
Presentation at AIDSImpact 2011, Santa Fe, 12-15 September
Schenk,Katie D.; Friedland,Barbara A.; Apicella,Louis; Sheehy,Meredith; Munjile,Kelvin; Hewett,Paul C.
Publication date: 2011

Acceptability of the vaginal microbicide Carraguard® among couples in Chiang Rai, Thailand (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Martin,Sarah; Blanchard,Kelly; Manopaiboon,Chomnad; Chaikummao,Supaporn; Schaffer,Kate; Friedland,Barbara A.; Kilmarx,Peter H.
Publication date: 2008

An analysis of varying measures of adherence among women enrolled in the Carraguard® Phase 3 trial (PDF
Presentation at Microbicides 2008, New Delhi, 24-27 February
Littlefield,Sarah A.; Gehret,Marlena; Friedland,Barbara A.; Maguire,Robin A.; Govender,Sumentheran N.; Vilakazi,Hlengiwe; Carolus,N.; Rossier,Jasmine; Sibanyoni,F.; Modise,J.; Palanee,Thesla; Ramjee,Gita; de Kock,Alana; Ahmed,Khatija
Publication date: 2008

An evaluation of care and support of women who test HIV positive during the Phase 3 Carraguard® trial in South Africa (PDF
Presentation at Microbicides 2008, New Delhi, 24-27 February
Harries,Jane; Patel,Smruti; Cassim,Nazira; Friedland,Barbara A.; Ahmed,Khatija; Mtimkulu,Vuyelwa; Palanee,Thesla; Morar,Neetha S.; Milford,C.
Publication date: 2008

Challenges and results of including 16-17-year-old women in the Carraguard® Phase 3 efficacy trial (PDF
Presentation at Microbicides 2008, New Delhi, 24-27 February
Skoler,Stephanie; Friedland,Barbara A.; Gehret,Marlena; Ngcozela,N.; Mthembu,P.N.; Palanee,Thesla; de Kock,Alana; Ahmed,Khatija; Malebo Ratlhagana,Mary-Jane
Publication date: 2008

Challenges implementing behavioral research in microbicides clinical trials  
Presentation at Microbicides 2008, New Delhi, 24-27 February
Abbott,Sharon; Friedland,Barbara A.; de Kock,Alana; Harries,Jane; Morar,Neetha S.; Madiba,Sphiwe; Katzen,Lauren L.
Publication date: 2008

Decision making and the influences of others in the informed consent process: A qualitative investigation in the Phase 3 study of Carraguard® (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Abbott,Sharon; Friedland,Barbara A.; Katzen,Lauren L.; de Kock,Alana; Madiba,Sphiwe; Cishe,Sheila
Publication date: 2008

Evaluation of a video to enhance the informed consent process in the Phase 3 Carraguard® trial (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Friedland,Barbara A.; Skoler,Stephanie; de Kock,Alana; Katzen,Lauren L.; Apicella,Louis; Williams,Manuela M.; Mehlomakulu,Vuyelwa; Mtimkulu,Vuyelwa
Publication date: 2008

Exploring microbicide acceptability in terms of socio-cultural norms, relationships, and product attributed in the Carraguard® Phase 3 trial in South Africa  
Poster presentation at XVII International AIDS Conference, Mexico City, 3-8 August
Abbott,Sharon; de Kock,Alana; Morar,Neetha S.; Friedland,Barbara A.; Mtimkulu,Vuyelwa; Cishe,Sheila; Madiba,Sphiwe; Phillip,Jessica; Gehret,Marlena; Mokgatle,Mathila
Publication date: 2008

Impact of acceptability on adherence in the Carraguard® Phase 3 trial (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Friedland,Barbara A.; Littlefield,Sarah A.; Skoler,Stephanie; de Kock,Alana; Palanee,Thesla; Gehret,Marlena; Katzen,Lauren L.; Morar,Neetha S.; Mehlomakulu,Vuyelwa; Williams,Manuela M.
Publication date: 2008

Incidence and point prevalence of sexually transmitted and reproductive tract infections among women enrolled in the Phase 3 Carraguard® trial in South Africa (PDF
Presentation at Microbicides 2008, New Delhi, 24-27 February
Palanee,Thesla; Gehret,Marlena; Skoler,Stephanie; Lahteenmaki,Pekka; Friedland,Barbara A.; Patel,Smruti; Ahmed,Khatija; Cassim,Nazira; Altini,Lydia; Morar,Neetha S.; Govender,Sumentheran N.; Zhou,Lifen; Ramjee,Gita
Publication date: 2008

Male partner circumcision and HIV seroconversion among participants in the Phase 3 Carraguard® microbicide trial (PDF
Presentation at Microbicides 2008, New Delhi, 24-27 February
Gehret,Marlena; Palanee,Thesla; Skhosana,Joseph; Friedland,Barbara A.; Littlefield,Sarah A.; de Kock,Alana; Williams,Nela; Skoler,Stephanie
Publication date: 2008

Male partner involvement in the Carraguard® Phase 3 trial: Data from a qualitative study of the informed consent process (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Madiba,Sphiwe; Friedland,Barbara A.; Abbott,Sharon; Katzen,Lauren L.; de Kock,Alana; Cishe,Sheila
Publication date: 2008

Qualitative evaluation of the informed consent process in the Phase 3 Carraguard® efficacy trial: Study staff experiences and recommendations for future trials (PDF
Poster presented at Microbicides 2008, New Delhi, 24-27 February
Katzen,Lauren L.; Friedland,Barbara A.; Abbott,Sharon; de Kock,Alana; Madiba,Sphiwe; Cishe,Sheila
Publication date: 2008

What motivates women to enroll in vaginal microbicide clinical trials: Results from the Phase III Carraguard trial  
Poster presentation at XVII International AIDS Conference, Mexico City, 3-8 August
Abbott,Sharon; Friedland,Barbara A.; Katzen,Lauren L.; Madiba,Sphiwe; de Kock,Alana; Cishe,Sheila
Publication date: 2008

Engaging participants in a Phase 3 study of the efficacy and safety of the microbicide Carraguard® in preventing HIV seroconversion in women (abstract)  
Presentation at 3rd South African AIDS Conference, Durban, 5-8 June
de Kock,Alana; Morar,Neetha S.; Williams,Nela; Friedland,Barbara A.; Skoler,Stephanie; Mtimkulu,Vuyelwa; Ngcozela,Veronica; Gumede,Sicelo; Mehlomakulu,Vuyelwa; Govender,Sumentheran N.
Publication date: 2007

Health concerns and HIV risk perception as motives to join a clinical trial  
Presentation at 36th Annual Psychosocial Workshop, New Orleans, April
Abbott,Sharon; Friedland,Barbara A.; Katzen,Lauren L.
Publication date: 2007

Microbicides update  
Presentation on the status of the Population Council's microbicides development efforts
Friedland,Barbara A.
Publication date: 2005

Community participation in a Ga-Rankuwa/Soshanguve Phase 3 Carraguard trial  
Poster at Microbicides 2004, London, 28-31 March
Molete,Dimakatso; Malebo Ratlhagana,Mary-Jane; Marumo,Mabitso; Mohlatlego,Sebola; Pistorius,Annalie; Hoosen,Anwar; Friedland,Barbara A.; Skoler,Stephanie
Publication date: 2004

Development of a recruitment video for a Phase 3 trial of Carraguard  
Presentation at Microbicides 2004, London, 28-31 March
Friedland,Barbara A.; Marumo,P.; de Kock,Alana; Skoler,Stephanie; Ngcozela,Veronica; Monedi,C.; McGrory,C.Elizabeth; van de Wijgert,Janneke
Publication date: 2004

Partner involvement in a phase III Carraguard trial  
Poster at Microbicides 2004, London, 28-31 March
Malebo Ratlhagana,Mary-Jane; Pistorius,Annalie; Molete,Dimakatso; Friedland,Barbara A.; Skoler,Stephanie
Publication date: 2004

Ethical issues in microbicides testing  
Seminar given at Yale University Center for Interdisciplinary Research on AIDS (CIRA), May
Friedland,Barbara A.
Publication date: 2003

U.S. women's attitudes toward a potential microbicide  
Poster presentation at the Fourteenth Meeting of the International Society of Sexually Transmitted Diseases Research, Berlin, June
Friedland,Barbara A.; McGrory,C.Elizabeth
Publication date: 2001

Barbara Friedland, M.P.H.

Associate

Curriculum Vitae

Contact

E-mail: bfriedland@popcouncil.org

Address:
Barbara Friedland
Population Council
One Dag Hammarskjold Plaza
9th Floor
New York, NY 10017 USA
+1 212 339 0500

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