Population Council Research that makes a difference

Marc Goldstein, M.D.

Senior Scientist

Marc Goldstein is a senior scientist at the Population Council’s Center for Biomedical Research. He is internationally renowned for his pioneering work in vasectomy reversals and microsurgical repair of varicoceles and blockages and has performed over 1,000 microsurgical vaso-vasostomies and vaso-epididymostomies. He developed the microsurgical technique of varicocelectomy in 1984 and has performed over 3,000 procedures with the lowest reported failure and complication rates.

Goldstein has authored or co-authored over 200 journal articles and book chapters. He is the author of Surgery of Male Infertility (1995), the first textbook on the subject, and editor of Atlas of the Urologic Clinics of North America: Surgery for Male Infertility (1999) and Atlas of Clinical Urology: Infertility Section (1999). He co-authored the recently published A Baby At Last! The Couples' Complete Guide to Getting Pregnant—from Cutting-Edge Treatments to Commonsense Wisdom (Fireside Books/A Simon & Schuster Paperback) (PDF of news release). He is on the editorial boards of the medical journals Microsurgery and Journal of Andrology.

A summa cum laude graduate of the College of Medicine, State University of New York-Downstate Medical Center in Brooklyn, New York, Goldstein was trained in urology at Downstate Medical Center. He continued his postgraduate training in reproductive physiology at the Center for Biomedical Research and the Rockefeller University Hospital. In addition to his work at the Population Council, Goldstein currently is a professor of reproductive medicine and urology at Weill Medical College of Cornell University; surgeon-in-chief of male reproductive medicine and surgery at New York Weill Cornell University Medical Center; executive director of the Men’s Service Center of the Cornell Institute for Reproductive Medicine; and director of the Center for Male Reproductive Medicine and Microsurgery at the New York Weill Cornell University Medical Center.

Marc Goldstein, M.D.

Senior Scientist

Microsurgical spermatocelectomy: Technique and outcomes of a novel surgical approach  (abstract
Kauffman,Eric C.; Kim,Howard H.; Tanrikut,Cigdem; Goldstein,Marc
Journal of Urology 185(1): 238-242
Publication date: 2011

The Shang Ring device for adult male circumcision: A proof of concept study in Kenya  (abstract) (PDF) (HTML
Barone,Mark; Ndede,Frederick; Li,Philip S.; Masson,Puneet; Awori,Quentin; Okech,Jairus; Cherutich,Peter; Muraguri,Nicholas; Perchal,Paul; Lee,Richard; Kim,Howard H.; Goldstein,Marc
Journal of Acquired Immune Deficiency Syndromes 57(1): e7-e12
Publication date: 2011

A Baby At Last! The Couples' Complete Guide to Getting Pregnant -- from Cutting-Edge Treatments to Commonsense Wisdom  (PDF
Rosenwaks,Zev R.; Goldstein,Marc; Fuerst,Mark L.
Publication date: 2010

Infertility: The male 
Kim,Howard H.; Schlegel,Peter N.; Goldstein,Marc; Legato,Marianne J.
from Principles of Gender-Specific Medicine, pp. 366-380
Publication date: 2010

Male circumcision: Africa and beyond?  (abstract
Kim,Howard H.; Li,Philip S.; Goldstein,Marc
Current Opinion in Urology 20(6): 515-519
Publication date: 2010

No-needle local anesthesia for adult male circumcision  (abstract
Peng,Yifeng; Masson,Puneet; Li,Philip S.; Chang,Yue; Tian,Long; Lee,Richard; Kim,Howard H.; Sokal,David C.; Goldstein,Marc
Journal of Urology 184(3): 978-983
Publication date: 2010

Surgery for male infertility - Varicocelectomy and its alternatives 
Kim,Howard H.; Goldstein,Marc
from Clinical Andrology: EAU/ESAU Course Guidelines, pp. 105-115
Publication date: 2010

Varicocele repair for treatment of androgen deficiency  (abstract
Tanrikut,Cigdem; Goldstein,Marc
Current Opinion in Urology 20(6): 500-502
Publication date: 2010

A decision analysis of treatments for nonobstructive azoospermia associated with varicocele  (abstract
Lee,Richard; Li,Philip S.; Goldstein,Marc; Schattman,Glenn; Schlegel,Peter N.
Fertility and Sterility 92(1): 188-196
Publication date: 2009

High complication rates challenge the implementation of male circumcision for HIV prevention in Africa  (abstract
Kim,Howard H.; Goldstein,Marc
Nature Clinical Practice Urology 6(2): 64-65
Publication date: 2009

Male infertility in the era of ART: Why treat; how to treat 
Goldstein,Marc; Rosenwaks,Zev R.
Seminars in Reproductive Medicine 27(2): 107-108
Publication date: 2009

Obstructive azoospermia: A microsurgical success story  (abstract
Tanrikut,Cigdem; Goldstein,Marc
Seminars in Reproductive Medicine 27(2): 159-164
Publication date: 2009

Value of serum antisperm antibodies in diagnosing obstructive azoospermia  (abstract
Lee,Richard; Goldstein,Marc; Ullery,Brant W.; Ehrlich,Joshua; Soares,Marc; Razzano,Renee A.; Herman,Michael; Callahan,Mark A.; Li,Philip S.; Schlegel,Peter N.; Witkin,Steve S.
Journal of Urology 181(1): 264-269
Publication date: 2009

Adult varicocele  (abstract
Kim,Howard H.; Goldstein,Marc
Current Opinion in Urology 18(6): 608-612
Publication date: 2008

Reassessing reconstruction in the management of obstructive azoospermia: Reconstruction or sperm acquisition?  (abstract
Lee,Richard; Li,Philip S.; Schlegel,Peter N.; Goldstein,Marc
Urologic Clinics of North America 35(2): 289-301
Publication date: 2008

Innovative single-armed suture technique for microsurgical vasoepididymostomy  (abstract
Monoski,Mara A.; Schiff,Jonathan D.; Li,Philip S.; Chan,Peter T.K.; Goldstein,Marc
Urology 69(4): 800-804
Publication date: 2007

Simultaneous vasectomy and varicocelectomy: Indications and technique  (abstract
Lee,Richard; Li,Philip S.; Goldstein,Marc
Urology 70(2): 362-365
Publication date: 2007

Correlation of ultrasound-measured venous size and reversal of flow with Valsalva with improvement in semen-analysis parameters after varicocelectomy  (abstract
Schiff,Jonathan D.; Li,Philip S.; Goldstein,Marc
Fertility and Sterility 86(1): 250-252
Publication date: 2006

Haploinsufficiency at the protein kinase A RIα Gene Locus leads to fertility defects in male mice and men  (abstract
Burton,Kimberly A.; McDermott,Deborah A.; Wilkes,David; Poulsen,Melissa N.; Nolan,Michael A.; Goldstein,Marc; Basson,Craig T.; McKnight,G.Stanley
Molecular Endocrinology 20(10): 2504-2513
Publication date: 2006

Microsurgical reconstruction of iatrogenic injuries to the epididymis from hydrocelectomy  (abstract
Hopps,Carin V.; Goldstein,Marc
Journal of Urology 176(5): 2077-2080
Publication date: 2006

New developments in the evaluation and management of the infertile male 
Paduch,Darius A.; Goldstein,Marc; Rosenwaks,Zev R.; Oehninger,Sergio C.; Kruger,Thinus F.
from Male Infertility: Diagnosis and Treatment, pp. 453-460
Publication date: 2006

No-scalpel, no-needle vasectomy  (abstract
Monoski,Mara A.; Li,Philip S.; Baum,Neil D.; Goldstein,Marc
Urology 68(1): 9-14
Publication date: 2006

Varicocele: Size does matter 
Tanrikut,Cigdem; Goldstein,Marc
Journal of Urology 176(5): 1912-1913
Publication date: 2006

A practical approach to male infertility 
Hopps,Carin V.; Schlegel,Peter N.; Goldstein,Marc
from Principles of Gender-Specific Medicine, pp. 538-549
Publication date: 2004

Physiology of the testis and epididymis 
Robaire,Bernard; Hardy,Matthew P.; Chan,Peter T.K.; Goldstein,Marc; Rosenwaks,Zev R.
from Reproductive Medicine Secrets, pp. 15-22
Publication date: 2004

Robotic microsurgical vasovasostomy and vasoepididymostomy: A prospective randomized study in a rat model  (abstract
Schiff,Jonathan D.; Li,Philip S.; Goldstein,Marc
Journal of Urology 171(4): 1720-1725
Publication date: 2004

Effect of methylene blue, indigo carmine and renografin on human sperm motility  (abstract
Sheynkin,Yefim R.; Stamm,Christopher; Li,Philip S.; Goldstein,Marc
Urology 53(1): 214-217
Publication date: 1999

Restoration of spermatogenesis after scrotal replacement of experimentally cryptorchid rat testis: Assessment of germ cell apoptosis and eNos expression  (abstract
Zini,Armand; Abitbol,Joseph; Schulsinger,David; Goldstein,Marc; Schlegel,Peter N.
Urology 53(1): 223-227
Publication date: 1999

Varicocelectomy 
Brandell,Roy A.; Li,Philip S.; Goldstein,Marc
from Atlas of Urologic Clinics of North America: Surgery for Male Infertility, pp. 145-154
Publication date: 1999

Vasovasostomy 
Brandell,Roy A.; Li,Philip S.; Goldstein,Marc
from Atlas of Urologic Clinics of North America: Surgery for Male Infertility, pp. 45-64
Publication date: 1999

Germ cell apoptosis and endothelial nitric oxide synthase (eNOS) expression following ischemia-reperfusion injury to the testis  (abstract
Zini,Armand; Abitbol,Joseph; Girardi,Sarah K.; Schulsinger,David; Goldstein,Marc; Schlegel,Peter N.
Archives of Andrology 41: 57-65
Publication date: 1998

Induction of spermatogenesis and achievement of pregnancy after microsurgical varicocelectomy in men with azoospermia and severe oligoasthenospermia  (abstract
Matthews,Gerald J.; Matthews,E.D.; Goldstein,Marc
Fertility and Sterility 70(1): 71-75
Publication date: 1998

Surgical management of male infertility and other scrotal disorders 
Goldstein,Marc; Walsh,Patrick C.; Retik,Alan B.; Vaughan,E.Darracott,Jr.; Wein,Alan J.
from Campbell's Urology, pp. 1331-1377
Publication date: 1998

Marc Goldstein, M.D.

Senior Scientist

The Shang Ring for adult male circumcision: Evaluation of healing at three time intervals  
Presentation at First National Biennial HIV and AIDS Research Conference, Nairobi, 17-20 May
Awori,Quentin; Barone,Mark; Li,Philip S.; Otieno Simba,Raymond; Weaver,Mark A.; Cherutich,Peter; Muraguri,Nicholas; Wekesa,John; Nyanchoka,Jared; Perchal,Paul; Masson,Puneet; Lee,Richard; Goldstein,Marc; Sokal,David
Publication date: 2011

Pilot study of the Shang Ring: A novel male circumcision device for HIV prevention (abstract)  
Poster presentation at the XVIII International AIDS Conference, Vienna, 19 July
Barone,Mark; Ndede,Frederick; Li,Philip S.; Masson,Puneet; Cherutich,Peter; Muraguri,Nicholas; Wekesa,John; Perchal,Paul; Goldstein,Marc
Publication date: 2010

SUMOs and SUMOylation as promising targets for male contraceptive development in humans  
Presentation at The Future of Male Contraception, Seattle, 27-28 September
Brown,Petrice W.; Hwang,KeumSil; Mitchell,Lyann; Rapelje,Catherine; Goldstein,Marc; Schlegel,Peter N.; Morris,Patricia L.
Publication date: 2007

Marc Goldstein, M.D.

Senior Scientist

Curriculum Vitae