Population Council Research that makes a difference

Natalia Teleshova, M.D., Ph.D

Scientist

Natalia Teleshova is an immunologist at the Population Council's Center for Biomedical Research. Her laboratory analyzes the biological events in different mucosal surfaces that facilitate HIV infection and the influence of other sexually transmitted infections (STIs) on these events. Teleshova employs mucosal tissue explant models to address the key questions of virus–host interactions and immune responses in the setting of HIV infection with the goal to test strategies to prevent the spread of HIV and STIs.

Teleshova earned her M.D. from Pavlov State Medical University in St. Petersburg, Russia and her Ph.D. from the Karolinska Institute, Stockholm, Sweden. She conducted postdoctoral research at the Rockefeller University and the Population Council and received additional postdoctoral training at Mt. Sinai Medical Center in New York. Teleshova's postdoctoral research focused on the biology of HIV infection and its prevention through microbicides and vaccines.

Natalia Teleshova, M.D., Ph.D

Scientist

Nonclinical Laboratory Studies: Microbicide Formulation and Delivery (more)
Population Council laboratory scientists are developing vaginal rings and water-based gels to deliver microbicide formulations.
(1/2004 - ongoing)
Topics: HIV biomedical research; Microbicides
Countries: United States

Nonclinical Laboratory Studies: PC-1005 Gel (Carrageenan with Added MIV-150 and Zinc Salts) (more)
Council scientists are investigating microbicide gels containing carrageenan, MIV-150, and zinc salts that might block acquisition and transmission of HIV.
(1/2004 - ongoing)
Topics: HIV biomedical research; Microbicides
Countries: United States

Nonclinical Laboratory Studies: PC-700 Series Gels (Carrageenan with Zinc Salts) (more)
Council researchers are studying microbicide gels containing carrageenan and zinc salts that might block acquisition and transmission of herpes and HIV.
(1/2000 - ongoing)
Topics: HIV biomedical research; Microbicides
Countries: United States

Nonclinical Laboratory Studies: Vaginal Rings Loaded with MIV-150 (more)
Council scientists are conducting studies of vaginal rings releasing MIV-150 that might provide continuous protection from acquisition and transmission of HIV for at least one month.
(1/2007 - ongoing)
Topics: HIV biomedical research; Microbicides
Countries: United States

Role of Integrins in HIV/SIV Transmission Across the Cervico-Vaginal Mucosa (more)
Council researchers are studying the earliest stages of vaginal HIV infection in rhesus macaques.
(3/2012 - 3/2017)
Topics: HIV biomedical research
Countries: United States

Natalia Teleshova, M.D., Ph.D

Scientist

Simian immunodeficiency virus interactions with macaque dendritic cells  (HTML) 
Teleshova,Natalia; Derby,Nina R.; Martinelli,Elena; Pugach,Pavel; Calenda,Giulia; Robbiani,Melissa; Wu,L.; Schwartz,O.
from "HIV interactions with dendritic cells: Infection and immunity," Advances in Experimental Medicine and Biology 762 (Forthcoming), pp. 155-181
Publication date: 2013

The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT infection  (abstract) (PDF) 
Aravantinou,Meropi; Singer,Rachel; Derby,Nina R.; Calenda,Giulia; Mawson,Paul; Abraham,Ciby J.; Menon,Radhika; Seidor,Samantha; Goldman,Daniel; Kenney,Jessica; Villegas,Guillermo; Gettie,Agegnehu; Blanchard,James; Lifson,Jeffrey D.; Piatak Jr.,Michael; Fernandez-Romero,Jose A.; Zydowsky,Thomas M.; Teleshova,Natalia; Robbiani,Melissa
AIDS Research and Human Retroviruses 28(11): 1467-1475
Publication date: 2012

CpG-C ISS-ODN activation of blood-derived B cells from healthy and chronic immunodeficiency virus-infected macaques  (abstract) 
Teleshova,Natalia; Kenney,Jessica; Williams,Vennansha G.; Van Nest,Gary; Marshall,Jason; Lifson,Jeffrey D.; Sivin,Irving; Dufour,Jason; Bohm,Rudolf; Gettie,Agegnehu; Pope,Melissa
Journal of Leukocyte Biology 79(2): 257-267
Publication date: 2006

Dendritic cells and HIV infection: Activating dendritic cells to boost immunity  (abstract) 
Teleshova,Natalia; Kenney,Jessica; Robbiani,Melissa
Advances in Dental Research 19(1): 36-41
Publication date: 2006

Local and systemic effects of intranodally injected CpG-C immunostimulatory-oligodeoxyribonucleotides in macaques  (abstract) 
Teleshova,Natalia; Kenney,Jessica; Van Nest,Gary; Marshall,Jason; Lifson,Jeffrey D.; Sivin,Irving; Dufour,Jason; Bohm,Rudolf; Gettie,Agegnehu; Robbiani,Melissa
Journal of Immunology 177(12): 8531-8541
Publication date: 2006

CpG-C ISS-ODN activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-γ-secreting SIV-specific T cells  (abstract) 
Teleshova,Natalia; Kenney,Jessica; Jones,Jennifer; Marshall,Jason; Van Nest,Gary; Dufour,Jason; Bohm,Rudolf; Lifson,Jeffrey D.; Gettie,Agegnehu; Pope,Melissa
Journal of Immunology 173(3): 1647-1657
Publication date: 2004

Short-term Flt3L treatment effectively mobilizes functional macaque dendritic cells  (abstract) 
Teleshova,Natalia; Jones,Jennifer; Kenney,Jessica; Purcell,Jeanette; Bohm,Rudolf; Gettie,Agegnehu; Pope,Melissa
Journal of Leukocyte Biology 75(6): 1102-1110
Publication date: 2004

Immunodeficiency virus exploitation of dendritic cells in the early steps of infection  (abstract) 
Teleshova,Natalia; Frank,Ines; Pope,Melissa
Journal of Leukocyte Biology 74(5): 683-690
Publication date: 2003

Natalia Teleshova, M.D., Ph.D

Scientist

Functional myeloid and plasmacytoid dendritic cells in uninfected and infected rhesus macaques  
Poster presentation, AIDS Vaccine Meeting, New York, September
Teleshova,Natalia
Publication date: 2003