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Selected Publications

Akingbemi, Benson T., Renshan Ge, Qiang Dong, Chantal Sottas, Enmei Niu, and Matthew P. Hardy. Forthcoming. "Modulation of the male reproductive axis by an environmental antiandrogen, di (2-ethylhexyl) phthalate," in M.M. Aruldhas (ed.), Proceedings of the XXII Symposium on Reproductive Biology and Comparative Endocrinology.

Ge, Renshan, Qiang Dong, Chantal Sottas, Enmei Niu, Benson T. Akingbemi, and Matthew P. Hardy. Forthcoming. "The biology of Leydig cell development," in M.M. Aruldhas (ed.), Proceedings of the XXII Symposium on Reproductive Biology and Comparative Endocrinology.

Schlegel, Peter N., Marc Goldstein, and Matthew P. Hardy. Forthcoming. "Male reproductive biology," in Patrick C. Walsh et al. (eds.), Campbell’s Urology, 9th ed. New York: Saunders.

Ge, Renshan and Matthew P. Hardy. 2007. "Regulation of Leydig cells during pubertal development," in Anita H. Payne and Matthew P. Hardy (eds.), The Leydig Cell in Health and Disease. Totowa, N.J.: Humana Press.

Payne, Anita H. and Matthew P. Hardy (eds.). 2007. The Leydig Cell in Health and Disease. Totowa, N.J.: Humana Press. 

Ge, Renshan S., Qiang Dong, Chantal M. Sottas, Vassilios Papadopoulos, Barry R. Zirkin, and Matthew P. Hardy. 2006. "In search of rat stem Leydig cells: Identification, isolation, and lineage-specific development," Proceedings of the National Academy of Sciences of the United States of America 103(8): 2719–2724. (abstract)

Ge, Renshan S., Qiang Dong, Enmei Niu, Chantal M. Sottas, Dianne O. Hardy, James F. Catterall, Syed A. Latif, David J. Morris, and Matthew P. Hardy. 2005. "11β-hydroxysteroid dehydrogenase 2 in rat Leydig cells: Its role in blunting glucocorticoid action at physiological levels of substrate," Endocrinology 146(6): 2657–2664.

Ge, Renshan S., Qiang Dong, Chantal M. Sottas, Haolin Chen, Barry R. Zirkin, and Matthew P. Hardy. 2005. "Gene expression in rat Leydig cells during development from the progenitor to adult stage: A cluster analysis," Biology of Reproduction 72(6): 1405–1415.

Ge, Renshan, Qiang Dong, Chantal M. Sottas, Syed A. Latif, David J. Morris, and Matthew P. Hardy. 2005. "Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated," Molecular and Cellular Endocrinology 243(1–2): 35–42.

Hardy, Matthew P., Hui-Bao Gao, Qiang Dong, Renshan S. Ge, Qian Wang, Wei R. Chai, Xing Feng, and Chantal M. Sottas. 2005. "Stress hormone and male reproductive function," Cell and Tissue Research 322(1): 147–153.

Hardy, Matthew P. and Michael D. Griswold (eds.). 2005. Testicular Cell Dynamics and Endocrine Signaling, Annals of the New York Academy of Science, vol. 1061. New York: New York Academy of Sciences.

Latif, Syed A., Hector A. Pardo, Matthew P. Hardy and David J. Morris. 2005. "Endogenous selective inhibitors of 11β-hydroxysteroid dehydrogenase isoforms 1 and 2 of adrenal origin," Molecular and Cellular Endocrinology 243(1–2): 43–50.

Mukai, Motoko, Qiang Dong, Matthew P. Hardy, Hiroaki Kiyokawa, Richard E. Peterson, and Paul S. Cooke. 2005. "Altered prostatic epithelial proliferation and apoptosis, prostatic development and serum testosterone in mice lacking cyclin-dependent kinase inhibitors," Biology of Reproduction 73(5): 951-958

Weissman, Ben-Avi, Enmei Niu, Renshan S. Ge, Chantal M. Sottas, Michael Holmes, James C. Hutson, and Matthew P. Hardy. 2005. "Paracrine modulation of androgen synthesis in rat Leydig cells by nitric oxide," Journal of Andrology 26(3): 369-378.

Akingbemi, Benson T., Renshan S. Ge, Gary R. Klinefelter, Barry R. Zirkin, and Matthew P. Hardy. 2004. "Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances," Proceedings of the National Academy of Sciences of the United States of America 101(3): 775–780. (abstract)

Dong, Qiang and Matthew P. Hardy. 2004. "Leydig cell function in man," in S.J. Winters (ed.), Contemporary Endocrinology—Hypogonadism: Basic, Clinical and Therapeutic Principles. Totowa, NJ: Humana Press, pp. 23–44.

Dong, Qiang, Antonio Salva, Chantal M. Sottas, Enmei Niu, Michael Holmes, and Matthew P. Hardy. 2004. "Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress," Journal of Andrology 25(6): 973–981.

Morris, David J., Graham W. Souness, Syed A. Latif, Matthew P. Hardy, and Andrew S. Brem. 2004. "Effect of chenodeoxycholic acid on 11β-hydroxysteroid dehydrogenase in various target tissues," Metabolism 53(6): 811-816.

Robaire, B., and Matthew P. Hardy. 2004. "Physiology of the testis and epididymis," in P. Chan, M. Goldstein, and Z. Rosenwaks (eds.), Reproductive Medicine Secrets. Philadelphia: Hanley & Belfus, pp. 15–22.

Salva, Antonio, Matthew P. Hardy, Xiu-feng Wu, Chantal M. Sottas, David T. MacLaughlin, Patricia K. Donahoe, and Mary M. Lee. 2004. "Müllerian-inhibiting substance inhibits rat Leydig cell regeneration after ethylene dimethanesulphonate ablation," Biology of Reproduction 70(3): 600–607.

Wang, Gui-Min and Matthew P. Hardy. 2004. "Development of Leydig cells in the insulin-like growth factor-I (IGF-I) knockout mouse: Effects of IGF-I replacement and gonadotropic stimulation," Biology of Reproduction 70(3): 632–639.