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Senior Scientist Profile David M. Phillips is a senior scientist at the Population Council's Center for Biomedical Research; his expertise is in virology and reproductive biology. Over the last 17 years, Phillips's laboratory has conducted research on the sexual transmission of HIV that has led to the development of the Council's lead microbicide candidate, Carraguard®, which was recently tested in FDA-approved clinical trials. Today, his laboratory continues to investigate fundamental research on HIV, as well as developing novel second-generation microbicides and developing in vitro and animal systems for more advanced ways by which to assay microbicides. He also works on evaluating the safety and stability of candidate microbicides and the safety of rectal lubricants. Phillips received his Ph.D. at the University of Chicago, followed by a postdoctoral research appointment at Harvard Medical School. He joined the Population Council in 1973 to conduct fundamental research on sperm and fertilization. In the early 1980s when the HIV pandemic began to be recognized, Phillips developed an interest in HIV research. In 1987 he received a grant from the NIH to investigate the manner by which HIV is transmitted during sexual contact. Within a few years, he had identified candidate compounds that might be employed in a vaginal microbicide, one being carrageenan, the active ingredient in Carraguard.
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